Intramyocardial injection of hydrogel with high interstitial spread does not impact action potential propagation
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چکیده
منابع مشابه
The Different Mechanisms of Action Potential Propagation in the Heart
It was thought previously that cardiac muscle gap junctions provide low-resistance connections between cells and permit the local-circuit current to flow. Some evidences show that myocardial cells may not require low-resistance connections for successful propagation of the action potential (AP). It seems that some other types of mechanisms must be involved in AP propagation. In this article, we...
متن کاملThe Different Mechanisms of Action Potential Propagation in the Heart
It was thought previously that cardiac muscle gap junctions provide low-resistance connections between cells and permit the local-circuit current to flow. Some evidences show that myocardial cells may not require low-resistance connections for successful propagation of the action potential (AP). It seems that some other types of mechanisms must be involved in AP propagation. In this article, we...
متن کاملAction Potential Propagation
In the previous notes, we described the action potential for a “point” cell, so that we could use an ODE model. Here, we consider propagation of the action potential along an axon. Consider a system in which the intracellular and extracellular spaces are separated by a cell membrane. Let x be the one-dimensional spatial coordinate, and consider current conservation in the intracellular region c...
متن کاملthe different mechanisms of action potential propagation in the heart
it was thought previously that cardiac muscle gap junctions provide low-resistance connections between cells and permit the local-circuit current to flow. some evidences show that myocardial cells may not require low-resistance connections for successful propagation of the action potential (ap). it seems that some other types of mechanisms must be involved in ap propagation. in this article, we...
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Glia affect neural circuits in numerous ways. Microglia strip synapses and clear debris after injury; oligodendrocytes form myelin, which regulates axon conduction velocity and limits sprouting; and astrocytes direct blood flow to active circuits, provide nutrients and growth factors, regulate extracellular ion concentrations, guide neurite growth, promote synaptogenesis, stabilize dendritic sp...
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ژورنال
عنوان ژورنال: Acta Biomaterialia
سال: 2015
ISSN: 1742-7061
DOI: 10.1016/j.actbio.2015.08.004